منابع مشابه
Glucagon-like peptide-1, satiety and appetite control.
After eating a meal several subjective and behavioural changes occur. Normally hunger is reduced, the feeling of fullness increases and eating is inhibited. This state is called post-ingestive satiety: the inhibition of appetite resulting from food consumption. What mechanisms control this phenomenon? During and after eating there occurs a series of overlapping physiological responses, most of ...
متن کاملGlucagon-Like Peptide-1
Ma Glucagon-like peptide-1-(7-36) amide (GLP-1) is a human incretin hormone responsible for the release of insulin in response to food. Pre-clinical and human physiological studies have demonstrated cardioprotection from ischemia-reperfusion injury. It can reduce infarct size, ischemic left ventricular dysfunction, and myocardial stunning. GLP-1 receptor agonists have also been shown to reduce ...
متن کاملEffects of Fasting on Glucagon-like peptide-1 hormone (GLP-1), and Lipid Profile Indices in Obese and Thin Women
Introduction: Glucagon-like peptide-1 hormone (GLP-1) contributes to the regulation of insulin and glucose concentration. However, the effects of fasting on GLP-1 response in different people has not been determined yet. The aim of the present research was to investigate the effect of fasting on GLP-1 and the lipid profile of obese and thin women.Materials and methods: In this research, 25 obes...
متن کاملEffect of glucagon-like peptide-1 receptor antagonism on appetite and food intake in healthy men.
BACKGROUND Exogenous glucagon-like peptide-1 (GLP-1) inhibits eating in healthy, overweight, and diabetic subjects. OBJECTIVE The GLP-1 receptor antagonist exendin(9-39)NH2 (ex9-39) was used to further explore the role of GLP-1 as an endogenous satiation signal. DESIGN Two double-blind, 4-way crossover studies were performed, each of which included 10 healthy men. In study A, subjects recei...
متن کاملEffects of glucagon-like peptide 1 on appetite and body weight: focus on the CNS.
The delivery of nutrients to the gastrointestinal tract after food ingestion activates the secretion of several gut-derived mediators, including the incretin hormone glucagon-like peptide 1 (GLP-1). GLP-1 receptor agonists (GLP-1RA), such as exenatide and liraglutide, are currently employed successfully in the treatment of patients with type 2 diabetes mellitus. GLP-1RA improve glycaemic contro...
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ژورنال
عنوان ژورنال: Trends in Endocrinology & Metabolism
سال: 2013
ISSN: 1043-2760
DOI: 10.1016/j.tem.2012.11.008